摘要
Abstract
Objective To observe the affection of rosuvastatin on blood fat and arteriosclerotic plaque in patients with hypertension and hyperlipoidemia. Methods From September 2009 to September 2010, 98 cases of hypertensive with hyperlipoi-demia patients were randomly separated into two groups, which observation group with 49 cases was treated with rosuvastatin at basis of normal therapy. The changes of blood fat and arteriosclerotic plaque before and after treatment were observed. Results Compared with pre-treatment, the levels of TC, TG and LDL-C were significantly decreased, and HDL-C was significantly increased in observation group(P <0. 05) .while no significant difference in control group (P >0. 05). Moreover, the levels of TC, TG and LDL-C in observation group were significantly lower than those in control group, HDL-C was significantly higher than that in control group(P<0. 05). Compared with pre-treatment, the levels of LN and LMT were significantly decreased in observation group(P <0. 05 ) , while no significant difference in control group(P > 0. 05). Moreover, the levels of LN and LMT in observation group were significantly lower than those in control group (P <0. 05). The levels of LN and LMT were no significant differences in control group before and after treatment (P > 0. 05 ). Conclusion Rosuvastatin in treatment with patients with hypertension and hyperlipoidemia can low blood fat and arteriosclerotic plaque, which can be applied in clinic.关键词
瑞舒伐他汀/原发性高血压/高脂血症/血脂/动脉粥样硬化Key words
rosuvastatin/ hypertension/ hyperlipoidemia/ blood fat/ arteriosclerotic plaque分类
医药卫生
