山东科学2011,Vol.24Issue(6):49-52,4.
斑马鱼胚胎在毒理学研究中的应用
Application of zebrafish embryo in toxicology
王雪 1王希敏 1刘可春 1韩利文 1袁延强1
作者信息
- 1. 山东省科学院生物研究所,山东省生物传感器重点实验室,山东济南250014
- 折叠
摘要
Abstract
Zebrafish embryo is highly sensitive to chemical exposure and has much unique superiority over other animal models, so it is widely applied in toxicology. Besides chemical concentration, many other influences, such as chorion barrier, embryo exposure time, chemical characteristics and the interaction between different chemicals, should also be considered. Assessment methods of embryo toxicity are evolving from morphologic observation to molecular research, more emphasis on chemical mechanism. This makes zebrafish embryo have higher specificity and sensitivity in the toxicity detection.关键词
斑马鱼/胚胎/毒性Key words
zebrafish/embryo/toxicity分类
生物科学引用本文复制引用
王雪,王希敏,刘可春,韩利文,袁延强..斑马鱼胚胎在毒理学研究中的应用[J].山东科学,2011,24(6):49-52,4.