山东医药2011，Vol.51Issue(48)：30-32,3.
三阴性乳腺癌的临床病理特点及预后因素分析
Clinicopathological characteristics and prognosis factors of the triple-negative breast cancer
摘要
Abstract
Objective To analyze the clinicopathological characteristics and prognostic factors of the patients with triple-negative breast cancer (TNBC). Methods The datas of 111 TNBC patients were retrospectively analyzed. Clinicor pathological characteristics, prognostic factors and overall survival were surveyed. Results Of all the breast cancer cases registered in our hospital during this period, 111 TNBC patients accounted for approximately 9. 6% . TNBC occurred mostly in young women, with a median age of 46. 9 years. The tumor diameter ≥5 cm was in 24 patients (21. 6% ). The stage II (59.5% ) and stage Ⅲ (29. 7% ) were more common. Patients with the axillary lymph node metastasis accounted for 60.4% (67/111) , 40 (36. 0% ) patients presented metastases or recurrence. Univariate analysis suggested that tumor size, lymph node status and TNM stage were prognostic factors of TNBC. Cox multivariate analysis demonstrated tumor size and lymph node status were independent prognostic factor. Conclusion TNBC was a special subtype of breast cancer with a recurrence and poor prognosis.关键词
乳腺肿瘤/临床病理特点/预后Key words
breast neoplasms/clinicopathological characteristics/prognostic分类
医药卫生引用本文复制引用
刘剑仑,王日华,韦薇,杨华伟,蒋奕,黄真..三阴性乳腺癌的临床病理特点及预后因素分析[J].山东医药,2011,51(48):30-32,3.基金项目
广西自然科学基金项目(2011 GXNSFB018102). （2011 GXNSFB018102）
