生物骨科材料与临床研究2011，Vol.8Issue(6)：29-31,34,4.DOI:10.3969/j.issn.1672-5972.2011.06.010
降钙素原在急性创伤性脊髓损伤患者术后感染早期诊断的应用
Procalcitonin as an indicator in diagnosis of postoperative infectious complications in patients with acute traumatic spinal cord injury
黎华茂 1李敬中 1向峥 1林晓岗1
作者信息
- 1. 解放军一六一医院骨科,湖北武汉430012
- 折叠
摘要
Abstract
Objective To evaluate the effectiveness of procalcitoninC PCT ) in early diagnosis of postoperative infectious complications in patients with acute traumatic spinal cord injury. Methods Clinical data on 216 patients with acute traumatic spinal cord injury were perspectively collected, which included determination of PCT, CRP, WBC, and ESR preoperatively and 48 hours postoperatively. Then, we compared these laboratoryindicators between patients with and without postoperative infections. Results 22 participants developed postoperative infections, with the incidence rate of 10.2%. There were no significant differences between preoperative laboratory tests. At 48 hours after surgery, PCT (t=6.690,P＞=0.000 )and CRP (t=3.024, P=0.003 ) were significantly higher in infected patients than in those non-infected patients. Result of ROC showed that the effectiveness of PCT was superior to CRP in diagnosing postoperative infections. The best cut-off of PCT was 0.6ng/ml. Conclusions PCT is a reliable indicator in diagnosis of postoperative infection in patients with acute traumatic spinal cord injury, which can detect infection timely and guide treat strategy.关键词
降钙素原/创伤性脊髓损伤/术后感染Key words
Procalcitonin/ Traumatic spinal cord injury/ Postoperative infectious complications分类
医药卫生引用本文复制引用
黎华茂,李敬中,向峥,林晓岗..降钙素原在急性创伤性脊髓损伤患者术后感染早期诊断的应用[J].生物骨科材料与临床研究,2011,8(6):29-31,34,4.
