生物信息学2011，Vol.9Issue(4)：285-288,4.DOI:10.3969/j.issn.1672-5565.2011.04.05
甲型流感病毒基因组进化事件检测软件的实现
An application detecting evolutionary events of genomes of influenza A viruses
摘要
Abstract
Objective Antigenicity of influenza A virus was frequently shifted by cross - host transmission or reassort-tnent among human, swine and avian viruses. Traditionally, these evolutionary events were detected by evolutionary analysis that had shortcomings of complexity and being hard to set evolutionary algorithms and parameters. Methods We proposed a genotype profile method previously that overcame these shortcomings at some level. In the current paper, we developed a tool called "Tool for influenza A virus evolutionary events (IVEE) " implementing the genotype profile method. Results IVEE is an easy - to - use tool and can rapidly detect evolutionary events of genomes of influenza A viruses such as transmission and reassortment. Conclusion IVEE can be used to surveil virus evolution and be an application accompanying programs for evolutionary analysis.关键词
基因型谱/进化事件/迁移/重配Key words
genotype profile/ evolutionary events/ transmission/ reassortment分类
生物科学引用本文复制引用
应莉娅,袁东方,董长征..甲型流感病毒基因组进化事件检测软件的实现[J].生物信息学,2011,9(4):285-288,4.基金项目
国家自然基金(编号:31000594),浙江省教育厅基金(编号:Y200906182). （编号:31000594）
