陕西医学杂志2011，Vol.40Issue(12)：1655-1657,3.
LTS液基细胞学联合HPV16/18检测筛查早期宫颈癌的价值
The LTS liquid based cytology producer joint residue fluid HPV 16/18 in early cervical cancer screening test application value
兰淼 1李艳红 2朱少君 1巩丽 1韩秀娟 1任拼 1姚丽 1张伟1
作者信息
- 1. 第四军医大学唐都医院病理科,西安710038
- 2. 第四军医大学唐都医院妇产科,西安710038
- 折叠
摘要
Abstract
Objective > Explore the LTS liquid based cytology producer joint liquid based residual liquid HPV16/18 cervical cancer screening lesion before value of clinical application. Method t Using the LTS liquid based cells producer method to detect 1000 cases of patients with the mouth and obstetrics and gynecology cervical neck tube exfoliated cells and discharge,the remaining liquid based cells remain fluid HPV16/18 immune markmethod to detect. HPV16/18 positive and highly suspected patients with cervical lesions vaginal microscopically more biopsy, combined with the pathologic result analysis cervical lesions. Results: 1000 cases of sample analysis by the LTS detection in 870, 24 cases of ASCUS ASCUS-H 26 cases, LSIL 61 cases, H SIL 19 cases. 130 cases of vaginal cytology unusual person under mirror more tissue biopsies confirmed 71 cases of inflammatory, CINI18 example, CINII 21 example, CINIII 13 cases, invasive cancer in 3, 4 cases were wet wart. Immune markmethod to detect DNA found HPV16/18 infection rates for: normal or inflammation respectively 21. 1%, CINI16. 7 %, CINII 33. 3%, CINIII 69.2%, invasive cancer, wet wart 40.0% 100%. 65 cases of normal, HPV16/18 LTS positive patients with pathological test showed that inflammation 51 cases, CINI (19 cases), CINII5 cases. The LTS normal or inflammation and HPV16/18 positive patients with cervical lesions, the detection rate of 21. 5%. Conclusion: Liquid based cytology producer joint liquid based residual liquid HPV16 /18 cells detection can add cytology results, the screening early cer ical cancer to have the important meaning.关键词
子宫颈肿瘤 多相筛查/乳头状瘤病毒感染 液基细胞学检测Key words
Uterine cervical neoplasms Multiphasic screening Papillomavirus infections @Liquid based cell detection分类
医药卫生引用本文复制引用
兰淼,李艳红,朱少君,巩丽,韩秀娟,任拼,姚丽,张伟..LTS液基细胞学联合HPV16/18检测筛查早期宫颈癌的价值[J].陕西医学杂志,2011,40(12):1655-1657,3.
