实用肿瘤杂志2011，Vol.26Issue(6)：610-612,3.
鼻咽癌原发灶消退率与预后的关系
Relationship between tumor regression rate and long-term outcome in nasopharyngeal carcinoma
蒋春灵 1叶新芊 1李金高 1吴新生 1李国庆1
作者信息
- 1. 江西省肿瘤医院放疗科,江西南昌330029
- 折叠
摘要
Abstract
Objective To investigate the relationship between primary tumor regression rate and long-term outcome in nasopharyngeal carcinoma. Methods Ninty patients with primary nasopharyngeal carcinoma were treated with radiotherapy. Contrast-enhanced CT scan was performed before radiotherapy and in the middle of the course (36 -40 Gy). The tumor volume was calculated with square meter sum. The primary tumor volume was defined as Vo before radiotherapy and as Vjj during the course. The rate of regression was defined as R = (Vo - V* )/V0 x 100%. Results The overall 4-year local control rate ( LCR) , distant metastases-free survival ( DMFS), disease-free survival ( DFS) and overall survival (OS) were 90.3% , 81.2% , 71.5% and 81.6% , respectively. The 4-year LCR, DMFS, DFS and OS were 84.1% , 78.6% , 63.4% and 82.2% in HSG; 97.5% , 83.3% , 79.4% and 86.6% in MSG; and 90.4% , 82.2% , 71.5% and 77.6% in LSG. There were no significant differences in the 4-year LCR, DMFS, DFS and OS among the three groups ( All P > 0. 05 ). Conclusion There is no significant correlation between tumor regression rate and prognosis in patients with nasopharyngeal carcinoma receiving radiotherapy.关键词
鼻咽肿瘤/放射疗法/辐射耐受性/存活率/预后/治疗结果Key words
nasopharyneal neoplasms/radiotherapy/ radiation tolerance/ survival rate/ prognosis/ treatment outcome分类
医药卫生引用本文复制引用
蒋春灵,叶新芊,李金高,吴新生,李国庆..鼻咽癌原发灶消退率与预后的关系[J].实用肿瘤杂志,2011,26(6):610-612,3.
