生殖医学杂志2011，Vol.20Issue(z2)：71-74,4.DOI:10.3969/j.issn.1004-3845.2011.z2.013
Effects of short gamete co-incubation in human in vitro fertilization
Effects of short gamete co-incubation in human in vitro fertilization
摘要
Abstract
Traditionally oocytes have been exposed to sperm overnight for 16-20 h.This long period of co-incubation,however,has been shown to create problems with high levels of reactive oxygen species (ROS),which may affect embryo viability and cause hardening of the zona pellucida.Recently,several positive and negative effects of reducing the co-incubation time to 90-120 min were reported.The objective of this review was to discuss whether short exposure of oocytes to sperm in vitro might affect the clinical results and several problems arose in short gamete co-incubation.关键词
Fertilization/Gamete co-incubation/In vitro fertilization/Polyspermy/Reactive oxygen speciesKey words
Fertilization/Gamete co-incubation/In vitro fertilization/Polyspermy/Reactive oxygen species引用本文复制引用
Zeng Yong,Song Cheng,Zhang Wei..Effects of short gamete co-incubation in human in vitro fertilization[J].生殖医学杂志,2011,20(z2):71-74,4.基金项目
This work was supported by Innovation Program of ShenzhenHong Kong Collaboration (no.ZYB2009070907090141A) & Medical Scientific Research Foundation of Guangdong Province (no.A2009626,WSTJJ2009112844162219821214420X). （no.ZYB2009070907090141A）
