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三种不同剂型大黄对大鼠泻下作用的影响

窦倩 谢肄聪

天津中医药2011,Vol.28Issue(6):510-512,3.
天津中医药2011,Vol.28Issue(6):510-512,3.

三种不同剂型大黄对大鼠泻下作用的影响

Effect of three different preparations of rhubarb on purgative activity in rats

窦倩 1谢肄聪1

作者信息

  • 1. 天津医科大学总医院中医科,天津300052
  • 折叠

摘要

Abstract

[Objective] To study the effect of three different preparations of rhubarb on the purgative activity in rats. [Methods] The Wistar rats were randomly divided into four groups (n=10 in each group): normal group, superfine power group, granules group and traditional decoction pieces group. The rats were given with different preparations juice at a dose of 4 g/kg respectively by gavage daily, normal group was given with saline. The total excrements and the quantity of stools were observed, the level of stools and diarrhea index was calculated, and blood routine test and electrolytes were tested at last. [Results] There was difference in purgative activities among rats treated with three different preparations of rhubarb with equal doses. There was significant difference in purgative activities between the superfine power group and the traditional decoction pieces group. The effect of purgative activity of granules group was the worst. [Conclusion] The purgative activities induced by different preparations of rhubarb are different.

关键词

大黄/剂型/泻下作用

Key words

rhubarb/preparations/purgative activities

分类

医药卫生

引用本文复制引用

窦倩,谢肄聪..三种不同剂型大黄对大鼠泻下作用的影响[J].天津中医药,2011,28(6):510-512,3.

基金项目

乏津市科技创新专项资金项目(06FZZDSH00405). (06FZZDSH00405)

天津中医药

OACSTPCD

1672-1519

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