武警医学2012,Vol.23Issue(2):141-143,3.
乌鲁木齐维吾尔族与汉族前列腺癌骨转移的对比分析
Comparative analysis of bone metastasis in prostate cancer of Uygur and Han people in Urumqi region
冯希梅 1郭永荣2
作者信息
- 1. 830001,乌鲁木齐,新疆维吾尔自治区人民医院核医学科
- 2. 830001,乌鲁木齐,新疆维吾尔自治区人民医院骨二科
- 折叠
摘要
Abstract
Objective To analyze the characteristics of bone metastasis in prostate cancer of Uygur and Han people in Urumqi region in Xinjiang. Methods Bone scanning with SPECT was performed in 25 Uygur patients with prostate cancer ( Pca) and 41 Han patients with Pca. Serum osteocalcin was detected by radioimmunoassay. Serum total prostate - specific antigen (T - PSA) , free prostate specific antigen (F-PSA) , and the ratio (F/T) were detected by chemiluminescence immunoassay. Results The positive rate of bone scintigraphy was 52.0% (13 cases) in Uygur Pca patients and 75. 6% (31cases) in Han Pca patients, and the difference was statistically significant(P <0. 05) . The level of serum osteocalcin in Han Pca patients was significantly higher than that in the Uygur Pca patients (P <0. 05) . As to the level of F - PSA and T - PSA, there was not statistically significant difference between Uygur and Han Pca patients (P > 0. 05) . However, the ratio of F/T in Han Pca patients was significantly lower than that in the Uygur Pca patients (P<0.05). Conclusions There might be difference in bone metastasis in Pca between Uygur and Han people in Urumqi region in Xinjiang that clinicians should pay attention to.关键词
前列腺癌/骨转移/放射性核素骨显像/骨钙素Key words
prostate cancer/ bone metastasis/ radionuclide bone scintigraphy/ osteocalcin分类
临床医学引用本文复制引用
冯希梅,郭永荣..乌鲁木齐维吾尔族与汉族前列腺癌骨转移的对比分析[J].武警医学,2012,23(2):141-143,3.