武警医学2012，Vol.23Issue(3)：207-209,3.
肾细胞癌患者手术前后外周血T淋巴细胞亚群的变化及其临床意义
Variation and clinical significance of T lymphocyte subsets in peripheral blood of patients with renal cell carcinoma
管德辉 1王晓民 2苏宇 2王科亮 2徐万海2
作者信息
- 1. 150076,哈尔滨,武警黑龙江总队医院泌尿外科
- 2. 150001,哈尔滨医科大学附属第四临床医院泌尿外科
- 折叠
摘要
Abstract
Objective To observe the post - operative variation of immune function in patients with renal cell carcinoma and to investigate the significance of diagnosis and therapeutic effect evaluation by detecting the T - lymphocyte subset level in the peripheral blood of patients with renal cell carcinoma. Methods Thirty - nine patients with renal cell carcinoma were recruited between 2006 and 2009. The level of CD3 + , CD4 + , CD8 + , and CD4 + /CD8 + in the peripheral blood of these patients was detected by flow cytometry before and after operation and compared with that in control group. Results The level of CD3 + NCD4 + and CD4 + /CD8+ in patients with renal cell carcinoma was lower than in control group while the post - operative level of CD3 + 、CD4 + and CD4 + /CD8 + was significantly higher. Conclusions The pre - operative immune function in patients with renal cell carcinoma is inhibited to some extent. Detecting the T - lymphocyte subsets level in the peripheral blood of patients with renal cell carcinoma is of positive clinical significance for evaluation of the cell immue status, diagnosis of the disease and observation of the therapeutic effect.关键词
肾细胞癌/细胞免疫/T淋巴细胞亚群Key words
renal cell carcinoma/ cellular immunity/ T - lymphocyte subsets分类
医药卫生引用本文复制引用
管德辉,王晓民,苏宇,王科亮,徐万海..肾细胞癌患者手术前后外周血T淋巴细胞亚群的变化及其临床意义[J].武警医学,2012,23(3):207-209,3.
