外科理论与实践2012，Vol.17Issue(1)：17-20,4.
细针穿刺洗脱液测定甲状腺球蛋白鉴别转移淋巴结性质
Diagnosing cervical lymph node metastasis from papillary thyroid cancer by thyroglobulin measurement in fineneedle aspiration washout fluid
周好 1陈海珍 2陈曦 2余宁康 2陈诚 2吴志浩 2李宏为1
作者信息
- 1. 上海交通大学医学院附属瑞金医院外科,上海 200025
- 2. 上海交通大学医学院附属瑞金医院远洋分院外科,上海 200031
- 折叠
摘要
Abstract
Objective To investigate the feasibility of diagnosing cervical lymph node metastasis from papillary thyroid carcinoma (PTC) by thyroglobulin (Tg) assessment in fine-needle aspiration washout fluid. Methods Twenty patients with cervical lymph node metastasis from PTC were submitted to surgery department. The PTC lesions and enlarged lymph nodes were aspirated by fine-needle with Tg in washout fluid assayed and were diagonized pathologically. Results Among the cases, the median values of Tg in PTC [84.4 (19.0-446.1) ng/mL] did not differ from that in normal tissue [133.4 (16.0-558.3 ng/mL]. For the lymph node with diameter ＞1 cm, the level of Tg from metastatic lymph nodes [78.0 (14.9-1000.0) ng/mL] was significantly higher than that from inflammatory lymph nodes [0.1 (0.1-1.3) ng/mL]. Similar results were observed for the lymph nodes with diameter ＜ 1 cm [45.9 (8.0~352.0) vs 0.1 (0.1~2.1) ng/mL]. Tg from metastatic lymph nodes ＞ 1 cm was significantly higher than that from metastatic lymph nods ＜1 cm. However, no correlation was observed between Tg values in fine-needle washout and that in serum or the level of Tg antibody in serum. Conclusions Tg measurement in fine-needle aspiration washout fluid is effective to identify the characteristics of cervical lymph node in PTC patients.关键词
甲状腺乳头状癌/细针穿刺/甲状腺球蛋白/淋巴结转移Key words
Papillary thyroid cancer/Fine-needle aspiration/Thyroglobulin/Lymph node metastasis分类
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周好,陈海珍,陈曦,余宁康,陈诚,吴志浩,李宏为..细针穿刺洗脱液测定甲状腺球蛋白鉴别转移淋巴结性质[J].外科理论与实践,2012,17(1):17-20,4.
