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血清胱抑素C、高敏C反应蛋白与冠状动脉粥样硬化斑块负荷的关系

李庆 丁抗宁 王聪霞 董新 韩振华 魏瑾 张春艳 张岩 路艳 张荣

西安交通大学学报(医学版)2012,Vol.33Issue(1):43-47,5.
西安交通大学学报(医学版)2012,Vol.33Issue(1):43-47,5.

血清胱抑素C、高敏C反应蛋白与冠状动脉粥样硬化斑块负荷的关系

Correlation of serum levels of cystatin C and high-sensitivity C-reactive protein with coronary atherosclerotic plaque burden

李庆 1丁抗宁 1王聪霞 1董新 1韩振华 1魏瑾 1张春艳 1张岩 1路艳 1张荣1

作者信息

  • 1. 西安交通大学医学院第二附属医院心内科,陕西西安 710004
  • 折叠

摘要

Abstract

Objective To investigate the relationship of serum levels of cystatin C (CysC) and high-sensitivity C-reactive protein (hs-CRP) with coronary atherosclerotic plaque burden (CAPB). Methods A total of 120 patients who were suspected of coronary heart disease were included and screened by coronary angiography. The severity of coronary artery disease was evaluated by Gensini cumulative index. The extent of lesions was evaluated by Sullivan's methods; the correlation analysis was used to find the relationship of CysC and hs-CRP with Gensini score and CAPB. Results The serum level of CysC was significantly higher in unstable angina group than in stable angina group (P<0.05). The serum levels of CysC and hs-CRP were closely related to CAPB in univariate and multivariate analysis (P<0.05). Conclusion The serum levels of CysC and hs-CRP are significantly related to CAPB, and may be used as indicators for acute coronary events.

关键词

胱抑素C/高敏C反应蛋白/冠状动脉粥样硬化斑块负荷

Key words

cystatin C/ high-sensitivity C-reactive protein/ coronary atherosclerotic plaque burden

分类

医药卫生

引用本文复制引用

李庆,丁抗宁,王聪霞,董新,韩振华,魏瑾,张春艳,张岩,路艳,张荣..血清胱抑素C、高敏C反应蛋白与冠状动脉粥样硬化斑块负荷的关系[J].西安交通大学学报(医学版),2012,33(1):43-47,5.

基金项目

陕西省社会发展攻关计划(No.2009K17-04) (No.2009K17-04)

西安交通大学学报(医学版)

OA北大核心CSCDCSTPCD

1671-8259

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