中国组织工程研究2012，Vol.16Issue(5)：831-834,4.DOI:10.3969/j.issn.1673-8225.2012.05.017
大块异体骨联合自体骨髓移植修复股骨上段肿瘤切除后缺损
Massive bone allograft combined with autologous bone marrow transplantation for proximal femoral defects resulting from tumor resection
李波 1陈静 2阙祥勇 3陈文瑶 1李新志1
作者信息
- 1. 三峡大学仁和医院骨科,湖北省宜昌市,443001
- 2. 宜昌长航医院骨外科,湖北省宜昌市,443003
- 3. 三峡大学医学院形态学部,湖北省宜昌市,443002
- 折叠
摘要
Abstract
BACKGROUND:Bone defects due to bone tumor resection are difficult problems in clinic, and how to repair bone defects is a hotspot in the orthopedics.OBJECTIVE: To discuss the clinical application and effect of massive bone allograft combined with autologous bone marrowtransplantation for the defects after proximal femoral tumor resection.METHODS: From July 2000 to June 2005, a total of 12 patients with massive bone defects after proximal femoral tumorresections received irradiated frozen massive bone allograft combined with autologous bone marrow transplantation. The surgeryused “eggshell” technology similar to the spinal cord, femoral head was empty, the round ligament and cortical bone of thefemoral head was kept, as well as one third blood supply of the femoral head. Massive bone allograft combined with autologousbone marrow transplantation and internal fixation was performed.RESULTS AND CONCLUSION: Patients were followed-up regularly for 6-11 years after operation. The X-ray film showed thatvascularization and bone trabeculae crossing the host bone could be seen in 12 cases. In addition, the mean MSTS93 score of12 patients was 26.33, and the excellent rate of limb function was 83.3%. Massive bone allograft combined with autologous bonemarrow transplantation is an effective method for proximal femoral defects resulting from tumor resection and can integrate withthe surrounding host bone.关键词
骨肿瘤/同种异体/骨移植/骨缺损/骨髓移植分类
医药卫生引用本文复制引用
李波,陈静,阙祥勇,陈文瑶,李新志..大块异体骨联合自体骨髓移植修复股骨上段肿瘤切除后缺损[J].中国组织工程研究,2012,16(5):831-834,4.
