中国组织工程研究2012，Vol.16Issue(7)：1307-1310,4.DOI:10.3969/j.issn.1673-8225.2012.07.039
牙本质发育不全的硬组织研究与进展
Research and progress of dental hard tissues with dentinogenesis imperfecta
张莹 1邹静 2杨燃1
作者信息
- 1. 口腔疾病研究国家重点实验室,四川大学,四川省成都市,610041
- 2. 四川大学华西口腔医院儿童口腔科,四川省成都市,610041
- 折叠
摘要
Abstract
BACKGROUND: Dentinogenesis imperfecta is an autosomal dominant genetic disease with dysplastic dentin. Currently, moststudies on dentinogenesis imperfecta are focused on phenotype analysis and clinical therapy, while the reports on dental hardtissue of dentinogenesis imperfecta are rare.OBJECTIVE: To summarize the research progress of dental hard tissue with dentinogenesis imperfecta.METHODS: A computer-based online search of CNKI, PubMed and OVID databases was performed for related articles publishedbetween 1999 and 2011, with the key words of "dentinogenesis imperfecta, surface morphology, animal model, enamel dentinaljunction, dentinal tubule" in English and Chinese.RESULTS AND CONCLUSION: Most researchers recognize that the enamel of dentinogenesis imperfecta has normal structure.The lesions are located in enamel dentinal junction. The enamel dentinal junction represents a linear appearance. The dentinrepresents a structure disturbance with irregular calcification. The number of dentinal tubules reduces. The shape andarrangement of collagen fibers are abnormal. The reasons for the abnormal structures are not clear and need further research.关键词
牙本质发育不全/表面形态/动物模型/釉牙本质界/牙本质小管分类
医药卫生引用本文复制引用
张莹,邹静,杨燃..牙本质发育不全的硬组织研究与进展[J].中国组织工程研究,2012,16(7):1307-1310,4.
