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HPLC及LC-MS技术在低聚糖检测中的应用

杨成金 黄桦 黄永坤 张峻

现代科学仪器Issue(6):147-150,4.
现代科学仪器Issue(6):147-150,4.

HPLC及LC-MS技术在低聚糖检测中的应用

Application of HPLC and LC-MS in Determination of Oligosaccharides

杨成金 1黄桦 2黄永坤 3张峻2

作者信息

  • 1. 云南白药集团股份有限公司,云南昆明650118
  • 2. 昆明医学院第一附属医院,陆床药学中心,云南昆明650052
  • 3. 昆明医学院第一附属医院儿科云南,昆明650052
  • 折叠

摘要

Abstract

Objective The application of HPLC and LC-MS in the determination and analysis of oligosaccharides are introduced.Methods Relevant articles from China and abroad over the past decade are analyzed,arranged and summarized.Results HPLC can meet the requirements of separation,analysis and detection of different oligosaccharides by combining with various separation modes and detection methods.HPLC-MS will certainly increase the efficiency of separation and analysis.Conclusion HPLC and LC-MS have the advantages of high sensitivity,high selectivity and use extensively.With the daily improvement of HPLC and LC-MS,their applications in the determination and analysis of oligosaccharides will be more widely.

关键词

低聚糖/检测/高效液相色谱/液-质联用

Key words

Oligosaccharide/Determination/HPLC/LC-MS

分类

化学化工

引用本文复制引用

杨成金,黄桦,黄永坤,张峻..HPLC及LC-MS技术在低聚糖检测中的应用[J].现代科学仪器,2011,(6):147-150,4.

基金项目

国家科技支撑计划分课题 ()

现代科学仪器

OACSTPCD

1003-8892

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