畜牧兽医学报2011，Vol.42Issue(12)：1800-1804,5.
番鸭呼肠孤病毒病活疫苗诱导的免疫应答分析
The Study on Immunne Response of Muscovy Duck Reovirusis Alive Vaccine
摘要
Abstract
The experiment was conducted to access the effect of muscovy duck reovirusis alive vaccine on immune response and to explore the immune mechanism. After 1-day-old muscovy ducks were immunized, the growth and development were observed, neutralization antibody in the sera, proliferation responses of the lymphocytes in the peripheral blood, thymus and bursa cells to ConA and LPS, Cytotoxic activity of cytotoxic T lymphocytes (CTL) were detected. The results showed that the growth and development of the immunized muscovy ducks were more than that of control group. The neutralization antibody began to increase until 35 days. Lymphocyte proliferation response to ConA in blood and thymus was enhanced differently in the immunized muscovy ducks, but response to LPS in blood and bursa weren't changed differently. The cytotoxic activity of CTL in the immunized muscovy ducks was improved. So the muscovy duck reovirusis alive vaccine can improve the resistant ability of muscovy ducks to muscovy duck reovirus mainly by increasing cellular immunity. It laid theoretical basis on clinical application with muscovy duck alive vaccine.关键词
番鸭呼肠孤病毒病活疫苗/番鸭/免疫应答/细胞免疫Key words
muscovy duck reovirusis/alive vaccine/immunological response / cellular immunity分类
农业科技引用本文复制引用
林锋强,陈仕龙,陈少莺,朱小丽,程晓霞,胡奇林,王劭..番鸭呼肠孤病毒病活疫苗诱导的免疫应答分析[J].畜牧兽医学报,2011,42(12):1800-1804,5.基金项目
福建省畜牧重大专项(2006NZ003-2) （2006NZ003-2）
