西南国防医药2012，Vol.22Issue(3)：255-258,4.DOI:10.3969/j.issn.1004-0188.2012.03.009
高压氧联合甲钴胺治疗2型糖尿病周围神经病变的临床效果研究
Clinical effects of hyperbaric oxygen combined with mecobalamine on patients with type 2 diabetic peripheral neuropathy
汤涌 1张红梅1
作者信息
- 1. 430015,武汉,湖北省武汉市新华医院内分泌科
- 折叠
摘要
Abstract
Objective To investigate the clinical curative effects of hyperbaric oxygen combined with mecobalamine on patients with type 2 diabetic peripheral neuropathy( DPN ). Methods The 142 clinically selected patients with type 2 DPN were divided into control group and research group with 71 people in each group. Both groups received strict treatment regimen to control blood sugar. Meanwhile the control group received the treatment with mecobalamine,and the research group received hyperbaric oxygen combined with mecobalamine. Follow - up and analysis were made in clinical data of both groups,such as conduction velocity of sensory and motor nerves, H reaction latency, blood biochemical indicators and integrative curative effects. Results After the treatment, the conduction velocity of sensory and motor nerves in the research group increased significantly compared with those in the control group ( P <0. 05 ). Compared with the control group, the cholesterol, triglyceride, plasma viscosity, whole blood restore viscosity at low shear and random blood sugar level in the research group were significantly improved( P < 0. 05 ). The total effective rate of the control group was 63. 38% ,the research group was 85. 92% ,and the differences were significant between the two groups( P <0. 05 ). Conclusion Ischemia and anoxia are the main pathological changes of diabetic peripheral neuropathy. The therapy of hyperbaric oxygen combined with mecobalamine has good therapeutic effects on such diseases.关键词
2型糖尿病/周围神经病变/高压氧/甲钴胺Key words
type 2 diabetes/peripheral neuropathy/hyperbaric oxygen/mecobalamine分类
医药卫生引用本文复制引用
汤涌,张红梅..高压氧联合甲钴胺治疗2型糖尿病周围神经病变的临床效果研究[J].西南国防医药,2012,22(3):255-258,4.
