摘要
Abstract
Objective To compare the effect of blood oxygen level dependent (BOLD)-functional magnetic resonance imaging (fMRI) technique of healthy volunteers received needling sensation or not in right "Zusanli" , and to explore activation effect of acupoint needling on the central brain. Methods Twenty-two healthy volunteers were randomly divided into needling sensation group and non-needling sensation group, and received needling in right "Zusanli" (ST 36) respectfully, the ratio of the headcount of the two group is 3:1. The needling sensation group was stimulated by lifting and thrusting and rotating the acupuncture needle, while the non-needling sensation group was only by needling. Super magnetic resonance was used to scan the brain and the obtained experimental data in the regional brain were processed and analyzed by the method of Region of Interest(ROI). Results Many cerebral areas such as secondary somatosensory cortex(S Ⅱ), primal somatosensory cortex(S Ⅰ), left temporal cortex, insular cortex, motor cortex and supplementary, cingulategyrus, amygdaloid body, hypothalamus were activated in varying degrees in needling sensation groups. Only several cerebral areas were activated in non-needling sensation group, and significant difference was found between the two groups(P<0.01). Conclusion There was a relative difference for the activated cerebral area between needling sensation group and non-needling sensation group. Acupoint needling could activate special central cerebral areas.关键词
磁共振脑功能成像/针刺作用机制/足三里穴/足三里穴得气Key words
BOLD cerebral functional imaging/acupuncture/Zusanli(ST36)/needling sensation分类
医药卫生
