针刺研究2011，Vol.36Issue(6)：419-422,4.
电针“太冲”对轻症酒精性肝损伤大鼠的影响
Effect of Electroacupuncture of "Taichong"(LR 3) on Liver Function in Mild Alcoholic Liver Injury Rats
摘要
Abstract
Objective To observe the effect of electroacupuncture (EA) of "Taichong"(LR 3) on liver function in rats with mild alcoholic liver injury (MALI) so as to explore the feasibility of acupuncture in improving mild alcoholic liver injury. Methods Forty SD rats were randomly divided into control, model, EA-LR 3 and EA-non-acupoint groups (10 rats/group). MALI model was duplicated by intragastric administration of distillate spirit (14 mL/kg) for 12 hours. Rats of the control group were fed with the same volume of normal saline. EA (2 Hz, 6 V) was applied to bilateral "Taichong" (LR 3) and non-acupoint (the interspace between the 4th and 5th bones of toes in parallel with LR 3) for 30 min. Respectively. At the end of experiments, rats were sacrificed for collecting liver tissues. The activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST) of the liver supernatant were detected by using Lai's method. Results lln comparison with the control group, liver ALT and AST activities in the model group were increased significantly (P<0. 05), while in comparison with the model group, liver ALT and AST levels in the EA-LR 3 group were down-regulated remarkably (P<0. 05). No significant changes were found in liver ALT and AST level in the EA-non-acupoint group (P>0. 05). There was no significant improvement in the pathological changes of liver in the EA-LR 3 and EA-non-acupoint groups. Conclusion EA of "Taichong"(LR 3) may reduce distillate-spirit induced mild alcoholic liver injury in rats.关键词
电针/太冲/轻症酒精性肝损伤/丙氨酸氨基转移酶/天冬氨基酸氨基转移酶Key words
Electroacupuncture/ Taichong(LR 3)/ Mild alcoholic liver injury/ ALT/ AST分类
医药卫生引用本文复制引用
陈冰俊,张栋,李顺月,马惠敏,王淑友..电针“太冲”对轻症酒精性肝损伤大鼠的影响[J].针刺研究,2011,36(6):419-422,4.基金项目
国家中医药行业专项资助项目(No.200707022) （No.200707022）
