中国当代儿科杂志2012，Vol.14Issue(2)：93-96,4.
早产儿医院感染败血症的危险因素及病原学分析
Risk factors and pathogen distribution in premature infants with nosocomial sepsis
吴俊 1吴本清 1黄进洁 1罗亮 1唐沂1
作者信息
- 1. 暨南大学第二临床医学院/深圳市人民医院新生儿科,广东 深圳 518020
- 折叠
摘要
Abstract
Objective To investigate the main risk factors and pathogen distribution of nosocomial sepsis among premature infants. Methods The clinical data of 3418 hospitalized premature infants from January 2003 to December 2010 were retrospectively analyzed for the risk factors and pathogen distribution of nosocomial sepsis. Results The incidence of neonatal nosocomial sepsis was 3. 10% ( 106/3418) , and the median age at diagnosis of neonatal nosocomial sepsis was 19 (4-48) days. The major pathogens of the infections among these premature infants included gram-positive bacteria (45.2% ) , especially coagulase-negative Staphylococcus (24. 3% ) , and gram-negative bacteria (41. 7% ) , especially Klebsiella paeumoniae (25. 2% ) , as well as fungus (13.0%). Logistic regression analysis showed that the main risk factors included low birth weight, retention of central venous catheters, and long duration of parenteral nutrition ( OR: 3. 765 , 3. 051 , and 2. 998 , respectively; P < 0. 05 ). Conclusions Low birth weight, retention of central venous catheters, and long duration of parenteral nutrition are the main risk factors for neonatal nosocomial sepsis, whereas the leading pathogen is Klebsiella pneumoniae.关键词
医院感染/败血症/危险因素/早产儿Key words
Nosocomial infection/ Sepsis/ Risk factor/ Premature infant分类
医药卫生引用本文复制引用
吴俊,吴本清,黄进洁,罗亮,唐沂..早产儿医院感染败血症的危险因素及病原学分析[J].中国当代儿科杂志,2012,14(2):93-96,4.
