中国动脉硬化杂志2012,Vol.20Issue(1):85-88,4.
组织蛋白酶L与动脉粥样硬化
Cathepsin L and Atherosclerosis
摘要
Abstract
Cathepsin L is a cysteine protease with potent collagenolytic and elastinolytic activities and has increasingly prominent role in cardiovascular disease. In human carotid atheroma cathepsin L mainly accumulated in macropha-ges and mediated macrophages apoptosis, which led to plaque destabilization. In this article, the development of cathepsin L in atherosclerosis was reviewed.关键词
组织蛋白酶L/动脉粥样硬化/斑块Key words
Cathepsin L/ Atherosclerosis/ Plaque分类
医药卫生引用本文复制引用
贾小英..组织蛋白酶L与动脉粥样硬化[J].中国动脉硬化杂志,2012,20(1):85-88,4.基金项目
国家自然科学基金(30800449)以及湖南省卫生厅项目(C2008-012)资助 (30800449)