局解手术学杂志2012,Vol.21Issue(2):159-161,3.
重症急性胰腺炎合并急性呼吸窘迫综合征的临床分析
Clinical analysis of severe acute pancreatitis complicated with acute respiratory distress syndrome
宋扬 1刘全达 2沈洪2
作者信息
- 1. 解放军总医院急诊科,北京,100853
- 2. 解放军总医院肝胆外科,北京,100853
- 折叠
摘要
Abstract
Objective To investigate the clinical characteristics and treating experiences for patients of severe acute pancreatitis ( SAP ) complicated with acute respiratory distress syndrome ( ARDS ). Methods The clinical characteristics and outcomes of 40 patients of SAP complicated with ARDS between 2004 and 2007 were analyzed retrospectively. Results The Ranson score, APACHE II score, pancreatic CT severity index at admission and the number of dysfunctional organ at 72 hour after the onset of SAP were much higher for patients with ARDS than for those without ARDS ( P < 0. 01 ). The overall mortality was 21.5% ( 20/93 ) for patients with SAP, 35. 0% ( 14/40 ) for those combined with ARDS and 11.3% ( 6/53 ) for those without ARDS ( P <0. 01 ). Among SAP patients complicated with ARDS, the mortality was 55. 6% ( 10/18 ) for those occurring ARDS following the onset of ASP within 72 hours while it was 18. 2% ( 4/22 ) for those occurring ARDS following the onset of SAP after 72 hours ( P <0. 05 ). Their time intervals from SAP onset to death were ( 7. 3 ±5.0 ) days and ( 15.3 ±8.4) days, with significant differences, P < 0. 05. Conclusion The earlier ARDS combined with SAP occurs, the higher the mortality is. It could be beneficial to lower the mortality of SAP and to treat ARDS if close monitoring for patients at high risk and protective mechanical ventilation at early stage are performed.关键词
重症急性胰腺炎/急性呼吸窘迫综合征/多器官功能障碍综合征Key words
severe acute pancreatitis/acute respiratory distress syndrome/multiple organ dysfunction syndrome分类
医药卫生引用本文复制引用
宋扬,刘全达,沈洪..重症急性胰腺炎合并急性呼吸窘迫综合征的临床分析[J].局解手术学杂志,2012,21(2):159-161,3.