中国康复理论与实践2012，Vol.18Issue(3)：233-235,3.DOI:10.3969/j.issn.1006-9771.2012.03.011
家兔佐剂性关节炎疼痛前后痛觉P300的变化
Changes of Painful P300 in Rabbits with Adjuvant Induced Arthritis
卢惠苹 1张雷2
作者信息
- 1. 福建省福州市第二医院康复科,福建医科大学康复治疗系,福建福州市350007
- 2. 南京军区福州总医院,福建福州市350025
- 折叠
摘要
Abstract
Objective To explore the changes of the painful P300 under the state of pain induced by adjuvant induced arthritis (AIA) in rabbits. Methods The painful P300 and pain threshold in 10 rabbits were recorded before Freud's adjuvant injection, before and after morphine injection on the 7th day and the 21st day after Freud's adjuvant injection. Results With the pain threshold lowed (P<0.01), the latency of painful P300 was differentially shortened on the 7th day and 21st days after adjuvant injection (P<0.01). After morphine injected, pain threshold increased (P<0.01) and the latency of painful P300 was prolonged (P<0.01). On the 7th day, the amplitude of painful P300 differentially increased (P<0.05), and decreased (P<0.01) after morphine injected. The amplitude of painful P300 on the 21st day was significantly lower than that of the 7th day (P<0.01). The pain threshold correlated with the latency of painful P300 0=0.516, P<0.01). Conclusion Painful P300 is related with the condition of pain in rabbits with AIA.关键词
佐剂性关节炎/P300/痛觉诱发电位/波幅/潜伏期/痛阈Key words
adjuvant induced arthritis/P300/pain evoked potentials/amplitude/latency/pain threshold分类
医药卫生引用本文复制引用
卢惠苹,张雷..家兔佐剂性关节炎疼痛前后痛觉P300的变化[J].中国康复理论与实践,2012,18(3):233-235,3.
