摘要
Abstract
AIM: To investigate the analgesic effects of parecoxib sodium patient after surger-y. METHODS: 100 patients undergoing surgerywere randomly divided into two groups (n=50) : group P ( parecoxib sodium combined with PCEA) and group C (tramadol 0. 5 g combinedwith PCEA). All patients received PCEA after surgery respectively. VAS ( visible analgesia score) was performed within postoperative 4,6, 8,12 and 24 hours respectively,meanwhile,using frequency of PCA and the side effects were recorded as well. The levels of IL-6, TNF-a were detected at each time spots. RESULTS: Within postoperative 4,6, 8,12 and 24 hours, the VAS scores were all less in group P than those in group C(P<0. 05). The using frequency of PCA and the side effects were all less in group P thanthose in group C within 24 hours (P<0. 05). CONCLUSION: Parecoxib combined with PCEA after anorectic surgery has better analgesia effects and less side reactions. It reduces the ascension of IL-6, TNF-a in the perioperative period.关键词
帕瑞昔布钠/硬脊膜麻醉/外科手术/镇痛/不良反应Key words
Parecoxib sodium/ Patient controlled epidural analgesia/ Surgery/ Analgesia/ Adverse reaction分类
医药卫生
