中国临床药理学与治疗学2011，Vol.16Issue(12)：1426-1430,5.
何首乌中二苯乙烯苷的药效学和药动学研究进展
Progress of pharmacological effects and pharmacokinetics of stilbene glycoside from Polygonum multiflorum Thunb
摘要
Abstract
Stilbene glycosides, the special constituents in Polygonum multiflorum Thunb, were reported to be the active ingredients with various pharmacological effects. It is reviewed the research progress of the pharmacological effects of Stilbene glycoside (2,3,5,4 -tetra-hydroxystilbene-2-Oβ-D-glucoside) on antioxi-dant system, cardiovascular system, central nervous system and anti-tumor effects. The possible mechanism involved and its possible appli-cation are also discussed. Meanwhile, the advances in pharmacokinetics of stilbene glycoside such as absorption and metabolism are also summarized. Thus we can provide some new ideas and strategies for further in-depth research on stilbene glycosides.关键词
二苯乙烯苷/药效学/药动学Key words
Stilbene glycoside/Pharmacological effects/Pharmacokinetics分类
医药卫生引用本文复制引用
王健鲲,朱萱萱,孙建国..何首乌中二苯乙烯苷的药效学和药动学研究进展[J].中国临床药理学与治疗学,2011,16(12):1426-1430,5.基金项目
"重大新药创制"科技重大专项(2009ZX09304-001,2009ZX09502-004) （2009ZX09304-001,2009ZX09502-004）
