中国临床药理学杂志2012，Vol.28Issue(2)：88-90,3.
盐酸去甲乌药碱注射液在药物负荷核素心肌灌注显像中的有效性与安全性
Efficacy and safety of higenamine hydrochloride injection used in pharmacologicial stress myocardial perfusion imaging
田锐 1王蒨 1米宏志 1吕树铮 1柳弘 1周渊 1刘欣1
作者信息
- 1. 首都医科大学附属北京安贞医院心内科,北京100029
- 折叠
摘要
Abstract
Objective To observe the efficacy and safety of the hi-genamine hydrochloride injection compare with the injection drug load of adenosine in the myocardial perfusion imaging. Methods This clinical research was designed as a randomized, single - blinded study. All patients were divided into test group ( higenamine hydrochloride injection) and control group (the active drug adenosine) . All patients underwent coronary angiography. Evaluation of test drug on sensitivity, specificity, accuracy, positive predictive value and negative predictive value were performed. Adverse reactions were also observed during two drugs appli-cated. Results The validity and safety had no statistically significant difference between test group and control group in radionuclide myocardial perfusion imaging. Conclusion Higenamine hydrochloride injection is similar on the efficacy and safety compared with the injection drug load of adenosine in the myocardial perfusion imaging.关键词
冠状动脉疾病/经腔、经皮冠状动脉/药物负荷核素心肌灌注显像Key words
coronary artery disease/transluminal,percutaneous coronary/pharmacologic stress myocardial perfusion imaging分类
医药卫生引用本文复制引用
田锐,王蒨,米宏志,吕树铮,柳弘,周渊,刘欣..盐酸去甲乌药碱注射液在药物负荷核素心肌灌注显像中的有效性与安全性[J].中国临床药理学杂志,2012,28(2):88-90,3.
