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射频消融联合经动脉化疗栓塞治疗肝癌的疗效分析

孙贤俊 何胜利 沈婕 陈颢 陈越 蒋霆辉

中国临床医学2011,Vol.18Issue(6):803-808,6.
中国临床医学2011,Vol.18Issue(6):803-808,6.

射频消融联合经动脉化疗栓塞治疗肝癌的疗效分析

Transarterial Chemoembolization in Combination with Radiofrequency Thermal Ablation in Hepatocellular Carcinoma: a Systematic Review and Meta-analysis

孙贤俊 1何胜利 1沈婕 1陈颢 2陈越 3蒋霆辉3

作者信息

  • 1. 复旦大学附属肿瘤医院闵行分院肝胆胰中西医结合科,上海200240
  • 2. 复旦大学附属肿瘤医院中西医结合科,上海200032
  • 3. 上海中医药大学附属岳阳医院肿瘤介入科,上海200437
  • 折叠

摘要

Abstract

Objective: To compare the therapeutic effects of transcatheter arterial chemoembolization(TACE) plus radiofre-quency ablation(RFA) to TACE or RFA alone for hepatocellular carcinoma (HCC). Methods: All data of patients with HCC underwent TACE + RFA versus TACE or RFA were collected from literature by electronic searching and handwork searching. Meta-analysis that recommended by Cochrane Collaboration was done for the data above, 8 researches enrolled in criteria were included in this study using RevMan 4. 2. Results: Compared with that of TACE or RFA alone, 1-, 2-, 3- year survival in those underwent TACE + RFA was statistically higher (P<0. 05), Subgroup analysis showed: TACE + RFA group in lyear survival rate was no significant difference in RFA group, Compared with that of TACE alone, 1-, 2-, 3-year survival in those underwent TACE+ RFA was statistically higher(P<0. 001). Conclusions: The prospective efficacy of TACE plus RFA for HCC which can elevate the patients' survival rate is better than that of TACE or RFA alone.

关键词

肝癌/射频消融/经动脉化疗栓塞术/Meta分析/生存率

Key words

Hepatocellular carcinoma/ Radiofrequency ablation/ Transcatheter arterial chemoembolization) Meta-analysis/ Survival rate

分类

医药卫生

引用本文复制引用

孙贤俊,何胜利,沈婕,陈颢,陈越,蒋霆辉..射频消融联合经动脉化疗栓塞治疗肝癌的疗效分析[J].中国临床医学,2011,18(6):803-808,6.

基金项目

上海市闵行区科委课题(编号:2009MHZ022) (编号:2009MHZ022)

中国临床医学

OACSTPCD

1008-6358

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