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CD133蛋白在胆囊癌细胞株及胆囊癌组织中的表达

沈盛 艾志龙 潘洪涛 王越琦 锁涛 刘厚宝 童赛雄

中国临床医学2012,Vol.19Issue(1):6-7,2.
中国临床医学2012,Vol.19Issue(1):6-7,2.

CD133蛋白在胆囊癌细胞株及胆囊癌组织中的表达

Expression of CD133 in GBC Cell Line and in the Tissue of Gallbladder Carcinoma

沈盛 1艾志龙 1潘洪涛 1王越琦 1锁涛 1刘厚宝 1童赛雄1

作者信息

  • 1. 复旦大学附属中山医院普通外科,上海,200032
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摘要

Abstract

Objective:To investigate the expression of CD133 protein in gallbladder carcinoma cell line (GBC) and in the tissues of gallbladder carcinoma. Methods: Hocchst staining was performed to figure out the location of CD133 in GBC. Immuno-histochcmical staining was used to detect the expression of CD133 protein in the tissue samples of twenty patients with gallbladder carcinoma and twenty people with normal Gallbladders. Results; The results of Hocchst staining delineated that CD133 located in the cytoplasm and membrane of GBC. The expression of CD133 protein was detected in the tissues of gallbladder carcinoma by immunohistochemical staining and Western blotting, but not in the normal gallbladder tissues. Conclusions; CD133 protein is highly expressed in both the cell line and the tissues of gallbladder carcinoma.

关键词

CD133蛋白/人胆囊癌细胞株/人胆囊癌组织

Key words

CD133 protein/ Gallbladder carcinoma cell line/ Tissues of gallbladder carcinoma

分类

医药卫生

引用本文复制引用

沈盛,艾志龙,潘洪涛,王越琦,锁涛,刘厚宝,童赛雄..CD133蛋白在胆囊癌细胞株及胆囊癌组织中的表达[J].中国临床医学,2012,19(1):6-7,2.

基金项目

上海市卫生局科研基金项目(编号:2008145) (编号:2008145)

中国临床医学

OACSTPCD

1008-6358

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