中国临床医学2012，Vol.19Issue(1)：17-18,2.
还原型谷胱甘肽治疗行机械通气慢性阻塞性肺疾病患者的疗效
Effect of Reduced Glutathione on Mechanical Ventilation Used in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease
摘要
Abstract
Objective; To investigate the effect of reduced glutathionc on mechanical ventilation used in patients with acute exacerbations of chronic obstructive pulmonary discasc(COPD). Methods; A total of 47 cases of respiratory failure with COPD were divided into treatment groupCn - 22) and control group (n - 25). Both groups were given routine antibiotic, expectorant, draw gasps and nutritional support, 1. 8 g/d intravenous reduced glutathionc was given to the treatment group until weaning from mechanical ventilation or death. The changes in arterial blood gas before and after treatment, the duration of total mechanical ventilation, duration of hospital stay, intensive care unit (ICU) stay, survival rate were observed. Results; No significant difference was found in the changes in arterial blood gas of these two groups (P^>0. 05). Compared with treatment group, control group had shorter periods of mechanical ventilation, hospital stay and ICU stay. No significant difference was found in the survival rates of these two groups. Conclusions; Adding reduced glutathionc during mechanical ventilation can shorten the duration of ventilation, shorten the length of hospital and ICU stay, decrease the costs in hospital and improve the prognosis rate in COPD.关键词
还原型谷胱甘肽/慢性阻塞性肺疾病/机械通气Key words
Reduced glutathionc/ Chronic obstructive pulmonary disease/ Mechanical ventilation分类
医药卫生引用本文复制引用
张勇刚,李海明,赵兵,张华茹..还原型谷胱甘肽治疗行机械通气慢性阻塞性肺疾病患者的疗效[J].中国临床医学,2012,19(1):17-18,2.基金项目
河南省驻马店市科技发展计划项目(编号:20602) （编号:20602）
