中国临床医学影像杂志2012,Vol.23Issue(2):77-80,4.
遗忘型轻度认知障碍的弥散张量成像研究
The application of diffusion tensor imaging on 3.0T MR in amnestic mild cognitive impairment
黄婷婷 1刘鹏飞 1刘志兰 1刘丽娜1
作者信息
- 1. 哈尔滨医科大学第一临床医学院,黑龙江哈尔滨 150001
- 折叠
摘要
Abstract
Objective: To evaluate the fractional anisotrophy(FA) value of white matter in patients with amnestic mild cognitive impairment(Amci) and normal controls(NC) with diffusion tensor imaging(DTI) on 3.0T MR. Methods: Twenty-eight NC and 28 Amci who were diagnosed with Montreal cognitive assessment(MoCA) and minimental state examination(MMSE) scores underwent conventional MRI and DTI. FA values were measured in different brain regions with FiberTrak Package and then were compared between the two groups. Results: FA value decreased in both sides of parahippocampal gyrus, genu and sple-nium of corpus callusum in patients with Amci. Conclusions: Changes in the microstructure of the white matter integrity can be observed in patients with Amci, indicating that the DTI examination is helpful for early diagnosis of Amci.关键词
认知障碍/磁共振成像Key words
Cognition disorders/ Magnetic resonance imaging分类
医药卫生引用本文复制引用
黄婷婷,刘鹏飞,刘志兰,刘丽娜..遗忘型轻度认知障碍的弥散张量成像研究[J].中国临床医学影像杂志,2012,23(2):77-80,4.