中国美容医学2012，Vol.21Issue(2)：253-256,4.
A型肉毒毒素辅助额部皮肤软组织扩张的生物力学研究
Study on biomechanical characteristics of using botulinum toxin A in forehead expanded flap
鲍世威 1李森恺 2呼春晖 3李晓阳3
作者信息
- 1. 卫生部直属北京医院整形外科 北京100730
- 2. 中国医学科学院整形外科医院南二科
- 3. 北京工业大学机械工程与应用电子技术学院
- 折叠
摘要
Abstract
Objective Animal study is to investigate the biomechanics properties of using the botulinum toxin A to accelerate the expansion in forehead. Methods The bilateral chest and abdomen of every guinea pig was marked symmetrically in grid by tattoo. The botulinum toxin A was injected in cutaneous muscle of one side as the experimental group, the saline in other side as the control group. Implanted a 200ml expander beneath the cutaneous muscle on the bilateral chest and abdomen, and it was inflated 20ml each time, twice a week. After finished expansion, the specimens were obtained from the expanded flap and the capsule was resected. The stress-strain relationship, stress relaxation and creep of these specimens were tested by the material testing machine Instron4302. Results The viscoelasticity of the flap in the experimental group was better than the control group and similar to the unexpanded flap. In the same relaxation time.the flap in the experimental group was easy to relax than the control group. Keeping the same stress.the creep strain in the experimental group was less than the control group in the same period. Conclusion The botulinum toxin A can enhance the viscoelasticity of the expanded forehead flap.and make it similar to the unexpanded flap. It also can reduce the inflation resistance, accelerate the expansion,shorten the expansion period and enhance the area of expanded myocutaneous flap in forehead.关键词
A型肉毒毒素/额部皮肤软组织扩张/生物力学/应力-应变关系/应力松弛/蠕变Key words
botulinum toxin A/ expansion in forehead/ biomechanics/stress-strain relationship/ stress relaxation/ creep分类
医药卫生引用本文复制引用
鲍世威,李森恺,呼春晖,李晓阳..A型肉毒毒素辅助额部皮肤软组织扩张的生物力学研究[J].中国美容医学,2012,21(2):253-256,4.
