中国人兽共患病学报2011，Vol.27Issue(12)：1122-1125,4.
细菌性痢疾流行特点及志贺菌耐药性研究
The epidemic characteristics of Bacillary dysentery and drug resistance of Shigella
张国祥 1张传领 1沈利蒙 1楚旭1
作者信息
- 1. 浙江萧山医院临床检验中心,杭州311201
- 折叠
摘要
Abstract
To investigate the epidemic characteristics and antibiotic resistance of Shigella group causing Bacillary dysen-tery in patients in recent years for the guidance of clinical treatment and prevention and control of bacillary dysentery. Suspi-cious strains isolated from Shigella and Salmonella agar culture were identified to the group by VITEK-32 instrument and ser-um agglutination of bacteria, and K-B method was used to study the antimicrobial resistance. The test of paper confirm was used to studuy the producing extended-spectrum β-lactamases ( ESBLs), and three-dimensional test for detection AmpC β lacta-mases ( AmpC enzymes). Among 279 infected patients, the most common groups were Shigella sonnei (201 striains, account for 72.4%) and Shigella flexneri (76 strains, account for 27.2%), and the most infected patients were 0 to 11 year-old (ac-count for 71. 3% of the total infection rate, 199/279). High incidence from July to November. The results of antibiotic suscep-tibility test in vitro showed the resistance rates of Shigella flexneri and Shigella sonnei to ampirillin, piperacillin and cotri-moxazole were higher than 60%, and to ciprofloxacin and levofloxacin were low than 40% , In addition, no isolate was resistant to piperacillin/tazobactam and imipenem.151 strains were confirmed to be ESBLs positive (account for 54. 1% of the total in-fection rate, 151/279), but not AmpC enzyme. In our hospital, the major patient groups infected by Shigella flexneri and Shigella sonnei were infants and young children, and Shigella sonnei had an increasing tendency. The sensitivity of the two kind of Shigella to some antibiotics varied greatly. Therefore, clinician should selected reasonably antibiotics according to the bacteria identification and drug susceptibility of Shigella.关键词
志贺菌/耐药性/产超广谱β内酰胺酶Key words
Shigella/distribution drug resistanc/ extended-spectrum β-lactanmses (ESBLs)分类
医药卫生引用本文复制引用
张国祥,张传领,沈利蒙,楚旭..细菌性痢疾流行特点及志贺菌耐药性研究[J].中国人兽共患病学报,2011,27(12):1122-1125,4.
