中国人兽共患病学报2012，Vol.28Issue(1)：37-40,4.
猪源性乙型脑炎病毒分离株全基因序列测定和分析
Complete sequence analysis of Japanese encephalitis virus JX61 strain from swine
摘要
Abstract
In order to understand the genetic characteristics of Japanese encephalitis virus from swine, an JEV was isolated from swine, and its complete genome was sequenced and analyzed comparatively. The results of sequencing of the nucleo-tides demonstrated that the genome of strain JX61 was 10964 nucleotides in length with a single open reading frame encoding 3432 amino acids. Comparison of the complete genome sequences of different JEV isolates showed JX61 was 83. 6%-99. 3% nu-cleotide sequence homology among them, which resulted in 94. 9%-99. 6% amino acid sequence homology. Phylogenetic analysis through full-length genome showed that the JX61 strain belonged to genotype I . The phylogenetic analysis based on the entire genome demonstrated that JX61 strain has the nearest genetic relationship with XJP613 and the JX61 might belong to the genotype I. It was the first isolation of Japanese encephalitis virus genotype I from swine in Zhejiang province during recent years.关键词
乙脑病毒/序列分析/种系发生Key words
Japanese encephalitis virus/ sequence analysis/ phylogeny分类
医药卫生引用本文复制引用
赵灵燕,谢荣辉,朱函坪,徐芳,杨章女,姚苹苹,周小龙,朱智勇..猪源性乙型脑炎病毒分离株全基因序列测定和分析[J].中国人兽共患病学报,2012,28(1):37-40,4.基金项目
浙江省医药卫生科学研究基金项目(2008B 39) （2008B 39）
