中国水产科学2012，Vol.19Issue(1)：174-181,8.DOI:10.3724/SP.J.1118.2012.00174
雌雄半滑舌鳎脑垂体基因表达差异研究
Differential gene expression profiles between the pituitaries of female and male half-smooth tongue sole (Cynoglossus semilaevis)
摘要
Abstract
The half-smooth tongue sole (Cynoglossus semilaevis) is an important marine flatfish with significant potential for aquaculture in China. This species exhibits a typical sexual dimorphism in which males grow significantly slower and smaller than females. Thus, there is little economic benefit to culturing males. To improve our understanding of this sex-associated dimorphic growth phenomenon, we screened differentially expressed genes from the pituitary tissues of female and male half-smooth tongue sole using the Affymetrix zebraf-ish microarray. A total of 486 genes were up-regulated and 561 genes were down-regulated. Based on standards for the relative strength of the difference (I.e., a ratio of the male to female hybridization signals of >1.5 or <0.6), we identifed 39 differentially expressed genes, including meis2.1, colla2, sh3gllb, actal, slc25a5,1/7, and acta2. Our results provide a foundation for investigating the molecular mechanisms controlling differential growth among the sexes.关键词
半滑舌鳎/生长二态性/脑垂体/基因芯片/差异表达基因Key words
Cynoglossus semilaevis/ sexual size dimorphism/ pituitary, microarray/ gene expression profiles分类
农业科技引用本文复制引用
柳淑芳,马骞,马慧,孙中之,柳学周,庄志猛..雌雄半滑舌鳎脑垂体基因表达差异研究[J].中国水产科学,2012,19(1):174-181,8.基金项目
国家自然科学基金(30871913) （30871913）
山东省泰山学者工程专项(2009.03-2014.02). （2009.03-2014.02）
