中国实验动物学报2011,Vol.19Issue(6):544-547,4.DOI:10.3969/j.issn.1005-4847.2011.06.019
转基因动物在毒理学中的应用
Use of transgeneic animals in toxicology
摘要
Abstract
Transgeneie animals play an important role in researches of gene functions related to regulation of metabolism, cell differentiation and growth, etc. In the new drug development and investigation, transgenic animal models have been a useful tool of non-clinic safety evaluation and rapid screening. In this article we will review the commonly used transgenic mice and rats in toxicology, and to briefly discuss the significance of transgenic animals in toxicological studies.关键词
转基因动物/模型,动物/毒理学Key words
Transgenic animal/ Model, animal/ Toxicology分类
生物科学引用本文复制引用
高虹,乔红伟..转基因动物在毒理学中的应用[J].中国实验动物学报,2011,19(6):544-547,4.基金项目
重大新药创制科技重大专项课题(2008ZX09305-001) (2008ZX09305-001)