中国比较医学杂志2012,Vol.22Issue(1):13-17,5.DOI:10.3969/j.issn.1671.7856.2012.001.004
Cramp过表达对小鼠骨髓造血干细胞功能的影响
Influence of Cramp Over Expression on the Function of Hematopoietic Stem Cell
摘要
Abstract
Objective to study the role of Cramp gene in the self-renew and differentiation of hematopoietic stem cells(HSCs). Methods cells from the bone marrow, spleen and thymus were analyzed by flow cytometry. HSCs were sorted and cultured in vitro. Results Compared with wild type mice, there are no great differences in the cell percentage and function of bone marrow, spleen and thymus in Cramp over expression mice. Conclusions Compared with the wild type mice, there was no great difference in the HSCs* differentiation and single cell clone in Cramp over expression transgenic mice.关键词
Cramp过表达/转基因小鼠/骨髓造血干细胞Key words
Cramp over expression/ Transgenic mouse/ Hematopoietic stem cells分类
医药卫生引用本文复制引用
石桂英,陈显达,陈陟阳,马小茗,鞠振宇..Cramp过表达对小鼠骨髓造血干细胞功能的影响[J].中国比较医学杂志,2012,22(1):13-17,5.基金项目
中央级公益性科研院所基本科研业务费[ DWS201010 ]. ()