中国实用儿科杂志2011，Vol.26Issue(12)：920-923,4.
儿童重症监护病房感染病原菌分布及细菌耐药分析
Distribution and antibacterial resistance of pathogens in Pediatric Intensive Care Unit
胡海赘 1王春 1乔蓉 1张弘 1张育才1
作者信息
- 1. 上海市儿童医院上海交通大学附属儿童医院,上海200040
- 折叠
摘要
Abstract
Objective To investigate the tendency of bacterial distribution and drug resistance of pathgens in Pediatric Intensive Care Unit, then instruct clinical application of antibiotics reasonably. Methods The bacteria isolated from patients in PICU from Jan 2009 to Dec 2010 were identified by vitek 2 compact instrument and antibiotic susceptibility was determined by K-B disk diffusion method. Results A total of 657 pathogens strains were isolated, Gram-negative bacilli , Gram-postive cocci and fungi accounted for 69.9%, 23.4%, 6.7%, respectively. The most common pathogens of them were Pseudomonas aeruginosa (21.3%), then in series Acinetobacter baumannii (19.2%); the rate of the ESBL-produc-ing strains of Klebsiella pneumoniae and Escherichia coli was more than 70%, the ceftazidime and cefotaxime resisitant rates of ESBL-positive strains are more than 80%, the cefepime resisitant rate of ESBL-positive strains is more than 40%; the ceftazidime ? cefepime,, imipenenu meropenem resisitant rate of Acinetobacter baumannii are more than 75%; Staphy-loeoccus aurcus account for 5.0% , 29% strains of Staphyloeoccus aureus were Methicillin resistant S.aureus. The most common strains of fungi were Candida albicans (6.0%). All of them were sensitive to fluconazole, ketoconazole and am-photericin b. Conclusion The multi-drug resistance of pathogens are serious in PICU. It is important and urgent to carry out surveillance of bacterial resistance for appropriately using antibiotics.关键词
儿童重症监护病房/细菌分布/耐药性监测/抗生素Key words
pediatric intensive care unit, bacterial distribution, surveillance of drug resistance,antibiotics分类
医药卫生引用本文复制引用
胡海赘,王春,乔蓉,张弘,张育才..儿童重症监护病房感染病原菌分布及细菌耐药分析[J].中国实用儿科杂志,2011,26(12):920-923,4.
