摘要
Abstract
Objective To understand the prevalence of Epstein-Barr virus in hospitalized children. Methods All results of anti-VCA-IgM and anti-VCA-IgG to Epstein-Barr virus detected hy ELISA in Chongqing Children's Hospital from January to Deeemher in 2009 were collected. The data was counted using statistical analysis of Chi-Square Test by gender, age group and season. Results The total infection rate of Epstein-Barr virus for hoapitalized children under 18 years old was 35.27% in 2009 and the recent infection rate was 12.66% .The accumulation infection rate gradually increased with ages, and nearly half of children had been infected by Epstein-Barr virus in pre-school age group. The period from 3 to 5 years old was the peak age of infection. The accumulation rate among 0 ~ 3 months, 3 ~ 6 months, 6 ~ 12 months, 1-2 years, 3-5 years, 6-12 years and 13-18 years old was 27.70%, 10.48%, 14.13%, 27.69%, 44.61% , 51.99% and 57.34% , respectively. And the recent infection rate was 1.15% , 1.25% , 2.52% , 12.55% , 22.21%, 18.55% and 20.3%, respectively. The recent infection rates in March, September and October were higher than those of others in 2009, and the difference was statistically significant (P < 0.05). Except the 1 -2 years group (P < 0.05) , there was no difference in other age groups about the cumulative and the recent infection rate by gender (P > 0.05). Conclusion 1. The infection rate of Epstein-Barr virus for childen is lower than that reported before in China. Nearly half of children have been infected by Epstein-Barr virus in pre-school age group, the peak period of infection being 3- 5 years old.2. There is no gender difference of cumulative and recent infection rate in Chongqing in 2009, the infection rate in March and September-October were higher than those of others.关键词
儿童/EB病毒/血清流行病学/衣壳抗原Key words
child/ Epstein-Barr virus/ seroepidemiology/ capsid antigen分类
医药卫生
