中国实用妇科与产科杂志2012，Vol.28Issue(1)：53-55,3.
前列腺素类物质与宫缩乏力性产后出血的相关性
Correlativity between PGs (6-keto- PGF1α) levels and postpartum hemorrhage caused by uterine inertia
唐丽霞 1刘萍 1李文蕾 1方锦川 1邹璐 1周晓梅1
作者信息
- 1. 深圳市福田区妇幼保健院妇科,广东深圳518045
- 折叠
摘要
Abstract
Objective To study the relationship between PGs (6-keto-PGF1α、TXB2 ) levels and the amount of postpartum hemorrhage. Methods Adopted ELISA method to detect the levels of 6-keto- PGF1α and TXB2 in venous blood of 66 . Pregnant women ( postpartum hemorrhage 38 samples, non-postpartum bleeding 28 samples) and 28 samples of the child-bearing age healthy women in the women and child Health Institute Fntian of Shenzhen between Oct. 2008 and Oct. 2010. Results The levels of 6-keto- PGF1α : The levels of 6-keto- PGF1α of the postpartum bleeding group( 727. 89 ± 192. 17 ) ng/L was statistically higher than the group which was non-postpartum bleeding (530. 00 ± 212. 05) ng/L and the group of the childbearing age healthy women (450. 00 ±98. 15)ng/L (P < 0. 01) ; there was no significant differences in the levels of 6-keto- PGF1α between the group which was non-postpartum bleeding and the group of the childbearing age healthy women (P > 0. 05). The levels of TXB2: The levels of TXB2 of the postpartum bleeding group (249. 47 ± 80.45) ng/L was statistically lower than the group which non-postpartum bleeding(342. 86 ± 116. 44 ) ng/L (P < 0. 05), but was statistically higher than the group of the childbearing age healthy women (147. 14 ± 110. 86) ng/L( P < 0. 01). The levels of 6-keto- PGF1α was not correlated with the levels of TXB2 (r = 0. 076, P = 0. 76). Conclusion The higher expression of 6-keto- PGF1α and the lower expression of TXB2 might be one role of postpartum bleeding mechanism. PGs (6-keto-PGF1α、TXB2) is likely to become the early predictions for postpartum bleeding.关键词
产后出血/前列腺素类物质/6-酮-前列腺素F1α/血栓素B2Key words
postpartum bleeding/ PGs/ 6-keto-PGF1α/ TXB2分类
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唐丽霞,刘萍,李文蕾,方锦川,邹璐,周晓梅..前列腺素类物质与宫缩乏力性产后出血的相关性[J].中国实用妇科与产科杂志,2012,28(1):53-55,3.
