中国实用妇科与产科杂志2012，Vol.28Issue(2)：124-126,3.
非良性卵巢肿瘤保留生育功能治疗后妊娠相关问题分析
The pregnancy related problems after fertility-sparing therapy in non-benign ovarian tumor patients
王雁 1魏丽惠 1张晓红 1李艺 1王悦 1崔恒 1周蓉 1孙秀丽 1王世军 1王建六1
作者信息
- 1. 北京大学人民医院妇产科,北京100044
- 折叠
摘要
Abstract
Objective To investigate the factors related to the ability of pregnancy, maternal and fetal outcomes, and problems in prenatal care after fertility-sparing therapy in non-benign ovarian tumor patients. Methods Patients, who were treated with fertility-sparing therapy for borderline or malignant ovarian tumors in Peoples Hospital, Peking University between January 2000 and April 2010, not elder than 40-year-old, and nulliparous, were followed up. Only the patients who succeeded in following-up, wished to be pregnant, and had no contraception for more than 1 year were divided into pregnant and non-pregnant group for the statistical study. Results 57 patients meet to the criteria. Among them, 42 patients were succeeded in contact, and 23 patients were studied finally. 12 patients were pregnant, and 11 patients were non-pregnant. The median time from the last surgery or chemotherapy to pregnancy was 10 months ( range 3 ~ 60 months). The non-pregnant group had significant higher proportion in patients who were sterile before, or treated with staging surgery, or with more than stage I tumors than the pregnant group. The ratio of patients who were treated with oo-phorectomy in the non-pregnant group were higher than that of the pregnant group. The differences were statistically significant ( P ＜ 0. 05 ) . The common maternal and fetal complications were premature rupture of membrane, abortion, premature delivery and hyperbilirubinemia. 3 relapses in pregnant group were reported, of which, 2 happened during their late pregnancy. Conclusions The medical history of infertility, the type of conservative surgery, staging surgery or not, and stage may influence the pregnant ability of patients with borderline or malignant ovarian neoplasms after conservative treatment. Once pregnant, the prenatal care should be strengthened, in particular, the recurrence of tumors.关键词
卵巢癌/卵巢交界性肿瘤/保留生育功能手术/妊娠Key words
ovarian neoplasms/ borderline ovarian tumors/ conservative surgery/ pregnancy分类
医药卫生引用本文复制引用
王雁,魏丽惠,张晓红,李艺,王悦,崔恒,周蓉,孙秀丽,王世军,王建六..非良性卵巢肿瘤保留生育功能治疗后妊娠相关问题分析[J].中国实用妇科与产科杂志,2012,28(2):124-126,3.
