中国实用妇科与产科杂志2012，Vol.28Issue(2)：127-130,4.
超声联合肿瘤标志物预测附件包块良恶性质的临床价值
The clinical value of ultrasound combined with tumor markers in predicting adnexal masses
陶洁 1赵肖波 1孙静 1陈萍 2汪希鹏1
作者信息
- 1. 同济大学附属第一妇婴保健院 妇科,上海 200040
- 2. 同济大学附属第一妇婴保健院 超声科,上海 200040
- 折叠
摘要
Abstract
Objective To assess the value of preoperative ultrasonography combined with tumor markers in predicting benign or malignant adnexal mass. Methods Between Jan. 2009 and Oct. 2010, 475 patients with adnexal mass underwent surgery in Shanghai First Maternal and Infant Hospital. Tumor morphology derived from ultrasonographic images, tumor size , tumor bilaterality, tumor markers, and patient demographics were evaluated preoperatively and compared with paraffin pathologic diagnosis. Multivariable classification and regression tree analysis were used to predict benign or malignant adnexal mass. Result Among 475 patients in this study, 100 patients with ovarian cancer, 50 with borderline ovarian tumors and 325 with benign ovarian tumors were certified by final paraffin diagnosis. Tumor morphology was classified into cystic, solid or complex by ultrasonography. 144 (78. 7% ) of 183 cystic adnexal masses were benign, 19 (10. 4% ) were malignant. 160 (64.8%) of 247 complex adnexal masses were benign, 58 (23.5%) were malignant. 21 (46. 7% ) of 45 solid adnexal masses were benign, 23 (51. 1% ) were malignant. Risk of malignancy in a complex or solid adnexal mass was significantly higher than that in cystic mass ( P ＜ 0. 001) . Ovarian Cancer Predicting Model 1,2, 3 were designed. Model 1 :CA125 ≥35kU/L combined with solid or complex mass in tumor morphology. Model 2:CA125 ≥100kU/L combined with solid or complex mass. Model 3 :CA125≥35kU/L and CA199≥37kU/L combined with solid or complex mass. Conclusion The complex and solid echo of ultrasonographic images combined with CA125 (35kU/L could predict malignancy disease of ovary efficiently.关键词
附件包块/彩色多普勒超声/CA125/预测Key words
adnexal mass/ Doppler ultrasonography/ CA125 / prediction分类
医药卫生引用本文复制引用
陶洁,赵肖波,孙静,陈萍,汪希鹏..超声联合肿瘤标志物预测附件包块良恶性质的临床价值[J].中国实用妇科与产科杂志,2012,28(2):127-130,4.
