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首页|期刊导航|中国兽医科学|重组禽流感H5亚型二价灭活疫苗(H5N1 Re-4+Re-5株)抗体消长规律及免疫程序的研究

重组禽流感H5亚型二价灭活疫苗(H5N1 Re-4+Re-5株)抗体消长规律及免疫程序的研究

范根成 左青山 王红 刘东 冯阳 李祥瑞

中国兽医科学2011,Vol.41Issue(12):1253-1259,7.
中国兽医科学2011,Vol.41Issue(12):1253-1259,7.

重组禽流感H5亚型二价灭活疫苗(H5N1 Re-4+Re-5株)抗体消长规律及免疫程序的研究

Antibody response and vaccination schedule of bivalent killed avian influenza vaccine of H5 subtype(Re-4+Re-5)

范根成 1左青山 2王红 2刘东 2冯阳 2李祥瑞3

作者信息

  • 1. 南京农业大学动物医学院,江苏南京210095/青岛易邦生物工程有限公司,山东青岛266032
  • 2. 青岛易邦生物工程有限公司,山东青岛266032
  • 3. 南京农业大学动物医学院,江苏南京210095
  • 折叠

摘要

Abstract

The antibody changes against Re-5 and Re-4 of SPF chickens,commercial layer,layer breeders,and broiler were observed post the vaccination with bivalent reassortment of H5 subtype avian influenza vaccine.The results indicated that the vaccination could induce high antibody responses.The antibody titer,high antibody titer and sustain time of high antibody titer were closely related to husbandry conditions and environment pollution.The vaccination result on broiler is not so satisfactory.Maternal antibody level influenced the vaccination result.The titer against Re-4 was 0.4 lb higher than that against Re-5.The results suggested that the vaccination program should be decided on the husbandry conditions,environment pollution,marketing time and weight of chickens.

关键词

禽流感/二价疫苗/免疫抗体

Key words

avian influenza/bivalent vaccine/immunization/antibody

分类

农业科技

引用本文复制引用

范根成,左青山,王红,刘东,冯阳,李祥瑞..重组禽流感H5亚型二价灭活疫苗(H5N1 Re-4+Re-5株)抗体消长规律及免疫程序的研究[J].中国兽医科学,2011,41(12):1253-1259,7.

基金项目

国家科技支撑计划项目(2006BAD06A08) (2006BAD06A08)

中国兽医科学

OA北大核心CSCDCSTPCD

1673-4696

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