中国实用外科杂志2012,Vol.32Issue(1):22-24,3.
肝脏移植后急性移植物抗宿主病的转化医学研究
The translational medicine study for acute graft-versus-host-disease after liver transplantation
摘要
Abstract
Translational medicine is a novel concept internationally and it focus on transferring achievement of basic research to clinical setting. The scientific idea of preclinical study often originates from clinical work. Acute graft-versus-host disease after liver transplantation is a challenging problem in the clinical practice because of its high mortality. The real mechanism of this disease is unclear at present. Since its low incidence, it is necessary to document the mechanism experimentally. We did related research work in lab recently, which included rat model establishment, immune problem and modalities exploring et al. The preclinical research results are pending to apply in clinicalsetting. Our work is a typical example of translationalmedicine. From this view point, here we summarize someissues.关键词
转化医学/肝移植后急性移植物抗宿主病/调节性T细胞Key words
translational medicine/ acute graft-versus-host disease after liver transplantation/ regulatory T cells分类
医药卫生引用本文复制引用
梁廷波,夏雪峰..肝脏移植后急性移植物抗宿主病的转化医学研究[J].中国实用外科杂志,2012,32(1):22-24,3.基金项目
国家自然科学基金杰出青年基金项目(No.30925033) (No.30925033)
浙江省卫生高层次创新人才资助项目 ()