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肝脏移植后急性移植物抗宿主病的转化医学研究

梁廷波 夏雪峰

中国实用外科杂志2012,Vol.32Issue(1):22-24,3.
中国实用外科杂志2012,Vol.32Issue(1):22-24,3.

肝脏移植后急性移植物抗宿主病的转化医学研究

The translational medicine study for acute graft-versus-host-disease after liver transplantation

梁廷波 1夏雪峰1

作者信息

  • 1. 浙江大学医学院附属第二医院外科,浙江杭州310009
  • 折叠

摘要

Abstract

Translational medicine is a novel concept internationally and it focus on transferring achievement of basic research to clinical setting. The scientific idea of preclinical study often originates from clinical work. Acute graft-versus-host disease after liver transplantation is a challenging problem in the clinical practice because of its high mortality. The real mechanism of this disease is unclear at present. Since its low incidence, it is necessary to document the mechanism experimentally. We did related research work in lab recently, which included rat model establishment, immune problem and modalities exploring et al. The preclinical research results are pending to apply in clinicalsetting. Our work is a typical example of translationalmedicine. From this view point, here we summarize someissues.

关键词

转化医学/肝移植后急性移植物抗宿主病/调节性T细胞

Key words

translational medicine/ acute graft-versus-host disease after liver transplantation/ regulatory T cells

分类

医药卫生

引用本文复制引用

梁廷波,夏雪峰..肝脏移植后急性移植物抗宿主病的转化医学研究[J].中国实用外科杂志,2012,32(1):22-24,3.

基金项目

国家自然科学基金杰出青年基金项目(No.30925033) (No.30925033)

浙江省卫生高层次创新人才资助项目 ()

中国实用外科杂志

OA北大核心CSCDCSTPCD

1005-2208

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