中国体外循环杂志2012，Vol.10Issue(1)：6-9,44,5.
低体重患儿围体外循环期实施新节约用血策略的研究
Application of a new blood saving strategy in low-weight infants with congenital heart disease during cardiopulmonary bypass
摘要
Abstract
Objective To evaluate the effect of a new blood saving strategy on reducing allogeneic blood transfusion and early postoperative prognosis in low - weight patients with congenital heart disease ( CHD ). Methods Seventy - six low - weight infants with CHD were divided into two groups since August in 2011 to January in 2012. In the control group ( n = 38 ), all infants were applied with conventional priming protocol with 2 u packed red blood cell ( PRBC ) and 100ml fresh frozen plasma ( FFP ); All infants in the experimental group ( n =38 ) underwent the new blood saving strategy with bloodless priming in cardiopulmonary bypass ( CPB ). The allogeneic blood transfusion in the two groups was collected respectively; the amount of chest - tube drainage during postoperative 24 hr and the changes of perioperative hemoglobin in each group were monitored. Results Each case in the experimental group was transfused with PRBC and FFP significantly less than that of in the control group ( P ＜ 0.01 ); Twelve cases in the experimental group underwent bloodless CPB, and the other 26 cases were added lu PRBC respectively during CPB, and no FFP were added in the CPB circuit. The chest - tube drainage during postoperative 24hr has no significant difference between the two groups ( P ＞ 0. 05 ); There was no significant difference between the two groups as to the mechanical ventilation and ICU stay time ( P ＞0.05 ). Conclusion The application of new blood saving strategy has a significant effect on reducing allogeneic blood transfusion, and also it has no side effect on the recovery of low weight infants. If the patients hemoglobin reached more than 120 g/L, the open heart surgery with bloodless CPB will be available.关键词
体外循环/婴幼儿/低体重/节约用血Key words
Cardiopulmonary bypass/ Infants/ Low - weight/ Blood saving分类
医药卫生引用本文复制引用
刘晋萍,王旭,龙村,冯正义,崔勇丽,赵举,赵明霞,胡金晓,李守军,闫军,晏馥霞..低体重患儿围体外循环期实施新节约用血策略的研究[J].中国体外循环杂志,2012,10(1):6-9,44,5.基金项目
国家自然科学基金(81100178) （81100178）
