中国体外循环杂志2012，Vol.10Issue(1)：16-19,35,5.
评估体外循环过程中三种血液回收设备对红细胞功能的影响
Comparison the effects of three Cell Saver devices on erythrocyte function during cardiopulmonary bypass procedure
王小华 1吉冰洋 1张燕婉 1孙燕华 1朱贤 1刘晋萍 1龙村1
作者信息
- 1. 100037,北京,北京协和医学院阜外心血管病医院体外循环科
- 折叠
摘要
Abstract
Objective Cell salvage devices are routinely used to process red blood cells ( RBCs ) shed during cardiac surgery. The purpose of this study was to evaluate three commercially available cell saver ( CS ) devices in terms of erythrocyte function and the quality of washed RBCs during cardiopulmonary bypass ( CPB ). Methods Thirty patients underwent CPB were randomly allocated to three CS devices: Group C ( Cell Saver 5 + ; Haemonetics, n = 10 ), Group M ( Autolog; Medtronic, n = 10 ), and Group F ( CATS; Fresenius HemoCare, n = 10 ). Blood samples were collected from reservoir and transfusion bag. Reservoirs and washed RBCs were analyzed for erythrocyte aggregation index ( AI ), deformation index ( DI ) and hematocrit viscosity ( HV ), 2, 3 - diphosphoglycerate (2,3- DPG ), hemotacrit ( Hct ), hemoglobin ( Hb ), free hemoglobin removal ( △ FHB ), glucose ( Glu ), lactate ( Lac ), as well as blood urea nitrogen ( BUN ). Results After processing, Group C ( P =0.026 ) and M ( P =0. 032 ) had relatively higher erythrocyte DI compare with Group F. Group C had lower A2, 3 - DPG comparing with Group M ( P =0. 001 ) and F ( P =0. 001 ). Group F provided the maximal concentration of Hct ( P = 0.021; 0.046 ) and Hb ( P = 0.008; 0.013 ). In addition, Group C ( P = 0.035 ) and M ( P =0.038 ) had the higher removal of FHB ( AFHB ) and had significant difference comparing with Group F. Conclusion CS devices use the same theory of centrifugation, however based on the different design, the function of the washed erythrocyte and undesirable content removal efficiency differs widely from one device to another.关键词
血液回收机/红细胞功能/体外循环/2,3-二磷酸甘油酸Key words
Cell saver/ Erythrocyte function/ Cardiopulmonary bypass/ 2, 3 - diphosphoglycerate分类
医药卫生引用本文复制引用
王小华,吉冰洋,张燕婉,孙燕华,朱贤,刘晋萍,龙村..评估体外循环过程中三种血液回收设备对红细胞功能的影响[J].中国体外循环杂志,2012,10(1):16-19,35,5.
