中国心理卫生杂志2011，Vol.25Issue(12)：910-914,5.DOI:10.3969/j.issn.1000-6729.2011.12.006
单一认知行为治疗对强迫障碍患者的疗效
Efficacy of single cognitive behavioral therapy for obsessive-compulsive disorder patients without medication
摘要
Abstract
Objective: To evaluate the efficacy and acceptability of cognitive behavioral therapy (CBT) based treatment manual for patients with obsessive-compulsive disorder (OCD). Methods: Seventeen patients who met the criteria for OCD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) were recruited to receive CBT treatment without medicatioa All the patients were free of psychoactive medication for at least 4 weeks before the study. The CBT treatments were based on a manual, including 12 individualized outpatient sessions on a weekly basis, administered by 3 trained CBT therapists. All subjects were evaluated with the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) by three psychiatrists independently on the treatment at the baseline and endpoint of the therapy. The patients did not receive any treatment except for CBT during the study. Results: Fourteen subjects completed 12 sessions of CBT. The dropout rate was 17.64%. At the end of the therapy, the Y-BOCS scores decreased from (22.4 ±5.9) to (9.7 ±6.0). The scores of HAMD and HAMA also reduced from (9.2 ±4.2) to (4.6 ±3.7), and (14.1 ±4.7) to (5.9 ±4.6) respectively (Ps <0.01). Based on the intention to treat principle, the response and remission rate were 70.6% (12/17) and 52.9% (9/17). Conclusion: It suggests that CBT based on the therapy manual could significantly improve obsessive-compulsive, anxiety and depressive symptoms for the drug-free patients with OCD. Meanwhile CBT is easy to be accepted by the patient and the compliance is good.关键词
认知行为治疗/强迫障碍/疗效Key words
cognitive behavioral therapy/ obsessive-compulsive disorder/ efficacy分类
医药卫生引用本文复制引用
罗佳,李占江,韩海英,徐子燕,郭志华,刘竞,熊红芳..单一认知行为治疗对强迫障碍患者的疗效[J].中国心理卫生杂志,2011,25(12):910-914,5.基金项目
北京市自然科学基金资助项目——强迫症CBT治疗前后的脑fMRI变化及与症状的关系(7082046) （7082046）
