中国斜视与小儿眼科杂志2011，Vol.19Issue(4)：149-152,4.
先天性白内障致形觉剥夺性弱视眼视网膜神经纤维层厚度分析
Analysis of retinal nerve fiber layer thickness in patients with form-deprivation amblyopia induced by congenital cataract
摘要
Abstract
Objective This study was designed to assess and compare the thickness of the peripapillary retinal nerve fiber layer (RNFL) and the fovea among normal children and children with form-deprivation amblyopi-a induced by congenital cataract. Methods OCT was performed on 82 children (142 eyes) with form-deprivation amblyopia induced by congenital cataract: Group A included 97 eyes with axial length 22.01 ~24.00mm; Group B included 45 eyes with axial length 24.01-29.00mm. Group C which has 18 normal children (36 eyes) took OCT also. The RNFL thickness were taken from the fovea and the peripapillary region. Results (1) Compared with group C, the retinal thickness of fovea were significantly thinner in eyes of amblyopic eyes, P<0.05, and the retinal thickness of fovea decrease with increasing of axial length, P<0.05. (2) Compared with group C, peripapillary RNFL thickness were significantly thinner in inferior, superior, nasal and the average thickness of the peripapillary RNFL in group B, P<0.05, while there were no significant differences in temporal and the thickness of fovea, P>0.05. Compared with group C, there are no statistically significant difference in thickness of every corresponding position of group A, P>0.05. Nasal peripapillary RNFL thickness in group A were significantly thinner than group B, P< 0.05. Conclusions There are significant abnormalities of retinal structure in form-deprivation amblyopia induced by congenital cataract.关键词
先天性白内障/形觉剥夺性弱视/光学相干断层扫描/视网膜神经纤维层Key words
form deprivation amblyopia/congenital cataract/optical coherence tomography/retinal nerve fiber layer引用本文复制引用
周薇薇,刘春民,苏满想,刘欣华,杜冰,冯其高..先天性白内障致形觉剥夺性弱视眼视网膜神经纤维层厚度分析[J].中国斜视与小儿眼科杂志,2011,19(4):149-152,4.基金项目
深圳市科技计划项目基金课题(200702087) （200702087）
