中国药房2011，Vol.22Issue(46)：4375-4376,2.
产超广谱β-内酰胺酶的大肠埃希菌和肺炎克雷伯菌所致医院感染的危险因素分析
Analysis of Risk Factors of Nosocomiai Infection Due to ESBLs-producing Escherichia coil and Klebsiella pneumoniae
摘要
Abstract
OBJECTIVE: To analyze the risk factors of nosocomial infection due to ESBLs-producing Escherichia coli {E.coli) and Klebsiella pneumoniae (K.pneumoniae). METHODS: 84 cases of nosocomial infection due to ESBLs-producing E. Coli and K. Pneumoniae and 168 cases of nosocomial infection which was not resulted from ESBLs-producing E.coli and K.pneumoniae were collected from 2008 to 2010 as case group and control group, respectively. The risk factors were analyzed by single factor and multiple factor Logistic regression analysis. RESULTS: Single factor analysis showed that the risk factors of nosocomial infection due to ESBLs-producing E.coli and K.pneumoniae were tracheal intubation or tracheotomy, indwelling catheter in vivo, use of lactamases inhibitor, quinolones and the third generation cephalosporins; while multiple factor Logistic regression analysis showed that tracheal intubation or tracheotomy, use of lactamases inhibitor, quinolones and the third generation cephalosporins were the independent risk factors of nosocomial infection due to ESBLs-producing E.coli and K.pneumoniae. CONCLUSION: Nosocomial infection due to ESBLs-producing E. Coli and K. Pneumoniae could attribute to multiple factors, which is mainly associated with use of antibiotics such as lactamases inhibitor, quinolones and the third generation cephalosporins, and invasive manipulation.关键词
产超广谱β-内酰胺酶的大肠埃希菌和肺炎克雷伯菌/医院感染/危险因素Key words
ESBLs-producing Escherichia coli and Klebsiella pneumoniae/ Nosocomial infection/ Risk factors分类
医药卫生引用本文复制引用
张骞峰,王爱民,孙增先,刘金勇..产超广谱β-内酰胺酶的大肠埃希菌和肺炎克雷伯菌所致医院感染的危险因素分析[J].中国药房,2011,22(46):4375-4376,2.基金项目
连云港市卫生局课题(09052) （09052）
