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参芪扶正注射液红外光谱质量控制方法研究

肖树雄 周清 钟桂雄 温金莲

中国药房2011,Vol.22Issue(47):4465-4467,3.
中国药房2011,Vol.22Issue(47):4465-4467,3.

参芪扶正注射液红外光谱质量控制方法研究

Study on Quality Control Method of Shenqi Fuzheng Injection by Infrared Spectroscopy

肖树雄 1周清 2钟桂雄 3温金莲2

作者信息

  • 1. 广东省药品检验所,广州市510180
  • 2. 广东药学院药科学院,广州市510006
  • 3. 丽珠集团利民制药厂,韶关市512028
  • 折叠

摘要

Abstract

OBJECTIVE: To establish a new quality control method for Shenqi fuzheng injection. METHODS: FT-IR spectro-metric technique was adopted to obtain spectrograms, and the second derivative and correlation coefficient of spectrograms were achieved by mathematical software. RESULTS: Infrared spectrograms of 10 batches of Shenqi fuzheng injection, 4 batches of Co-donopsis pilosula/Astragalus mongholicus,as well as their extractive, negative injection were obtained. The unique absorption peaks of Shenqi fuzheng injection were found, and the correlation coefficients of all injection were higher than 0.99. CONCLUSION: The method was low usage volume, convenient, quick and strong characteristics, and it could be applied in practical production.

关键词

参芪扶正注射液/红外光谱法/质量控制/党参/黄芪

Key words

Shenqi fuzheng injection/ Infrared spectroscopy/ Quality control/ Codonopsispilosula/ Astragalus mongholicus

分类

医药卫生

引用本文复制引用

肖树雄,周清,钟桂雄,温金莲..参芪扶正注射液红外光谱质量控制方法研究[J].中国药房,2011,22(47):4465-4467,3.

基金项目

2007年粤港关键领域重点突破项目(TC07BF09-11) (TC07BF09-11)

中国药房

OACSCDCSTPCD

1001-0408

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